MEDICATIONS WITH SIGNIFICANT ANTICHOLINERGIC PROPERTIES | |
Therapeutic Categories (Drug List*) | Potential Adverse Consequences |
Antihistamines • chlorpheniramine, cyproheptadine, diphenhydramine, hydroxyzine | Blood pressure, increased Breathing difficulty, changes Clumsiness or unsteadiness Convulsions Digestive system changes, e.g., • Bloating • Bowel motility, decreased • Constipation • Ileus, paralytic/adynamic • Nausea or vomiting • Swallowing difficulty with dry mouth Mental status/behavior changes, e.g., • Distress, excitement, nervousness • Attention, impaired • Cognitive decline • Confusion/disorientation • Hallucinations • Memory loss • Restlessness or irritability Delirium Dizziness or Drowsiness Fever Headache Heart rate, increased Lethargy, fatigue Mucous membrane dryness: mouth, nose Muscle weakness, severe Speech, slurring Skin, changes • Dryness • Sweating, decreased • Flushing • Warmth, excessive Vision impairment, changes in acuity • Blurring • Glaucoma, worsening • Eye pain • Light sensitivity Urinary retention or difficulty By Akshaya Srikanth, Pharm.D Intern, India |
Antidepressants • amoxapine, amitriptyline, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, paroxetine | |
Antipsychotics • chlorpromazine, clozapine, olanzapine, thioridazine | |
Antivertigo • meclizine, scopolamine | |
Cardiovascular • furosemide, digoxin, nifedipine, disopyramide | |
Gastrointestinal • Antidiarrheal: diphenoxylate atropine • Antispasmodics: belladonna, clidinium, chlordiazepoxide, dicyclomine, hyoscyamine, propantheline • Antiulcer: cimetidine, ranitidine | |
Muscle Relaxants • cyclobenzaprine, dantrolene, orphenadrine | |
Parkinsonism • amantadine, benztropine, biperiden, trihexyphenidyl | |
Urinary Incontinence • oxybutynin, propantheline, solifenacin, tolterodine, trospium ©akshaypharmd.blogspot.com |
Rabu, 15 Februari 2012
DRUGS WITH ANTICHOLINERGIC PROPERTIES
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